The U.S. healthcare industry is one of the fastest-growing markets globally, driven by an aging population, rising life expectancy, and an increasing focus on personalized care. For entrepreneurs, that means one thing: opportunity.
Healthcare franchises not only offer lucrative business models, but also give owners the chance to make a lasting impact on people’s lives. From home health to physical therapy, the demand for affordable, high-quality care is skyrocketing.
Whether you’re an entrepreneur exploring new industries or an investor looking for scalable growth, now is the time to explore the best healthcare franchise opportunities.
Below, we highlight the Top 5 Healthcare Franchises in the U.S. for 2023, each positioned to thrive in this booming market.
Want to explore ownership in one of the fastest-growing healthcare brands? Download our Free FYZICAL Investment Opportunity Guide to see if FYZICAL is right for you.
Headquarters: Sarasota, Florida
Locations: 600+ nationwide
Recognition:
FYZICAL is the fastest-growing physical therapy franchise in the U.S. and the world’s largest PT company. With over 600 locations, FYZICAL offers both traditional physical therapy (injury and surgery rehabilitation) and in-demand specialty services, including:
Physical therapy is experiencing explosive growth - $65.4 billion in 2025 projected to reach $128 billion in 2032 - due to:
In addition to rehabilitation, PT is now recognized as a cost-saving alternative to surgery, helping patients prevent injuries, strengthen mobility, and maintain long-term health.
FYZICAL’s proprietary Balance and Vestibular Program gives franchisees a powerful edge, offering industry-leading fall prevention therapies—a critical service for older adults.
FYZICAL offers multiple entry points for investors and clinicians:
With unmatched support, industry expertise, and scalable business models, FYZICAL dominates the physical therapy franchise space.
This makes FYZICAL not just a healthcare franchise, but a future-proof investment in one of the fastest-growing sectors of the U.S. healthcare industry.
With multiple entry points (single-unit, multi-unit, master franchise, and partnership programs), FYZICAL is more than a healthcare franchise—it’s a scalable investment platform. Start with a Territory Check today.
Headquarters: Omaha, Nebraska
Locations: 1,000+ franchises worldwide
Specialty: In-home senior care services
Home Instead is the largest senior care franchise in the world, delivering compassionate care that allows aging adults to remain in their homes while receiving essential support.
Their services include:
With 10,000 people turning 80 every day in the U.S., the demand for senior care is skyrocketing. Families are increasingly preferring in-home support over institutional care, making franchises like Home Instead both a profitable opportunity and a meaningful way to serve their communities.
Home Instead offers entrepreneurs the chance to own a business that:
Headquarters: Birmingham, Alabama
Founded: 1982 by Dr. D. Bruce Irwin
Locations: 400+ nationwide
Specialty: Urgent care, primary care, and occupational medicine
American Family Care pioneered the urgent care model as an alternative to long, impersonal ER visits. Since opening its first clinic in 1982, AFC has grown into one of the largest urgent care and family care networks in the U.S.
Services provided at AFC clinics include:
Patients increasingly want convenient, affordable, and fast healthcare solutions. AFC addresses this by offering same-day care, extended hours, and walk-in access—making it a go-to solution for busy families and working professionals.
As healthcare shifts toward urgent care and outpatient models, AFC is well-positioned at the forefront of this growing demand.
Owning an AFC clinic means tapping into:
Thinking more about physical therapy over urgent care? Read our blog on the Top 5 Physical Therapy Franchises in America to see how FYZICAL compares.
Headquarters: Scottsdale, Arizona
Locations: 800+ nationwide
Specialty: Affordable chiropractic care with a membership model
The Joint Chiropractic has redefined the chiropractic industry with a gym-style membership model that eliminates traditional barriers, such as insurance, referrals, and complicated scheduling. Patients benefit from:
Chronic back and neck pain affects millions of Americans each year. By offering a low-cost, accessible, and streamlined service, The Joint has tapped into a huge market of patients seeking non-invasive, drug-free relief for minor and moderate conditions.
With 800+ locations and growing, The Joint has become one of the largest and fastest-expanding chiropractic franchises in the U.S.
For entrepreneurs, The Joint offers:
Headquarters: Gurnee, Illinois
Founded: 2002
Locations: 400+ nationwide
Specialty: Home health care (medical and non-medical) + medical staffing
BrightStar Care is a leading home health franchise that provides a full spectrum of services—from skilled medical care to non-medical daily living assistance. Their comprehensive offerings include:
By serving both families and organizations, BrightStar has positioned itself as a versatile and resilient player in the healthcare franchise industry.
The U.S. is facing record demand for home-based healthcare services, driven by:
BrightStar addresses all three, making it a future-proof business model.
Franchisees benefit from:
Healthcare franchising is booming, and these five brands are leading the charge. Whether your passion is senior care, urgent care, chiropractic, or physical therapy, the opportunities are vast—but no segment is growing as quickly as PT.
With FYZICAL’s unmatched Balance Program, proprietary systems, and world-class support, the future of healthcare franchising is already here.
Check your territory today and join the brand redefining patient care and franchisee success.
People Also Ask:
How Much Does a Physical Therapist Make
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See Why Fyzical is a Top Low-Cost Franchise
FYZICAL Resources For You:
The Investment Opportunity Guide
Funding Your Physical Therapy Practice
The Physical Therapy Industry Report